A Fusion of Forces

The first of its kind, P.E.A.R.L. Advanced Cell Signaling System combines Exosomes (or Biosomes) and PDRN in a singular, in-office aesthetic treatment, synergizing and amplifying the positive effects of both for more radiant, restored skin.

inside the science

Rewriting Regenerative Skincare

Developed by the foremost experts in Exosome and Biosome technology, P.E.A.R.L. drives better cell-to-cell communication, teaching skin to actually behave like its younger self.


By boosting bioavailability, our system reignites collagen, improves texture and strengthens the skin’s barrier, giving way to visibly smoother, more resilient, radiant-looking skin.

Used in combination with an ablative service—think radiofrequency microneedling—P.E.A.R.L. delivers a true breakthrough in regenerative aesthetics.

Cutting-Edge Ingredients in Synergy

Each ingredient, intentionally selected for its targeted role, works in harmony as part of a multifaceted approach to cellular-level regeneration. 

P - PDRN
 A Salmon DNA derivative that boosts tissue regeneration and DNA repair, improving elasticity and hydration
E - Exosomes (or Biosomes)
 Accelerates healing and cell regeneration and stimulates collagen and elastin production
A - Antioxidants
 Brightens, evens tone and protects against UV damage and environmental stressors
R - Recombinant Growth Factors
 A bio-signal cocktail that firms and brightens
L - Amino Acids
 Supports hydration and promotes a stronger skin barrier, firmer texture, and faster repair

Highest Standards from Lab to Label

At AnteAGE®’s California headquarters, we adhere to academic best practices, following the International Society for Extracellular Vesicles’s (ISEV) guidelines and evolving our processes alongside breakthroughs in science, truly setting the bar in Exosome- and Biosome-specific sourcing and manufacturing.

EXOSOMES

The transmitters of transformation. Our hybrid-source Exosome solution features both bone marrow- and umbilical cord-derived mesenchymal stem cells (MSCs), which act as messengers of real, biological signals to drive cellular communication, coaching skin to repair from within.

BIOSOMES

Bioengineered for proven precision. Our Biosomes behave just as Exosomes do, but in a biosynthetic, lipid-based formula, ideal for those seeking a non-human-derived solution.

Experience the Power of P.E.A.R.L.

Schedule a consultation or treatment with a provider in your area today.